1. High-fat diet may lead to anxiety, depression

High-fat diet may lead to anxiety, depression

A high-fat diet may cause changes in brain that lead to anxiety and depression, new study has warned.

By: | Published: October 20, 2015 10:15 PM

A high-fat diet may cause changes in brain that lead to anxiety and depression, a new study has warned.

French researchers in experiments with mice found that increased body weight and high blood sugar as a result of consuming a high-fat diet may cause anxiety and depressive symptoms and measurable changes in the brain.

The beneficial effects of an antidepressant were blunted in mice fed a high-fat diet, researchers found.

“When treating depression, in general there is no predictor of treatment resistance,” said Dr Bruno Guiard, from the University of Paris-Sud and senior author of the study.

“So if we consider metabolic disorders as a putative treatment resistance predictor, this should encourage psychiatrists to put in place a personalised treatment with antidepressant drugs that do not further destabilise metabolism,” he said.

The study found that taking mice off a high-fat diet completely reversed the animals’ metabolic impairments and lessened their anxious symptoms.

“This finding reinforces the idea that the normalisation of metabolic parameters may give a better chance of achieving remission, particularly in depressed patients with type 2 diabetes,” said Guiard.

The study was published in the British Journal of Pharmacology.

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  1. Rebecca Schuster
    Oct 20, 2015 at 10:00 pm
    I used to be obese, so I know, it sucks. Although exercising works for some, it didn't for me so I tried different diets and it finally worked! You can see my review of the diet that worked on DietContent
    1. V
      Oct 21, 2015 at 10:27 am
      Not only fat everything in excess of need is bad not only fats. One need to decide quany for his consumption on the basis of his need that would further depend upon his life style in given cirstances. For a person working as a labor may need higher amount of food in comparison to those who need not to exert physically. That is a crucial factor in deciding the quantum of intake.

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