Branson said the trans-Pacific route, currently serviced only by Australian carrier Qantas and US airlines United and Hawaiian, was in "dire need of competition and a good shake-up."
His announcement comes weeks after Australia and the United States agreed to an "open skies" policy that allows Australian and US airlines to determine trans-Pacific routes and services independent of government involvement.
Branson said the launch of the daily V Australia flights would give the Virgin Group a global network for the first time.
"Flights to the United States are the obvious last piece of the puzzle," the British billionaire told reporters in Sydney.
Virgin Blue said that V Australia will add more US services to its daily schedule once it takes delivery of more new Boeing 777-300ER aircraft, adding that the airline was also looking at other international destinations.