According to local media reports, the newly married couple was going toward Hyderabad city from Karachi when the sorrowful accident took place on the highway.
The most popular drama of Sana Khan that was aired on ARY digital is Parchaiyaan.
The car flipped over as Babar Khan lost control of the vehicle.
Ambulances rushed the newly-wed couple to hospital, but Sana succumbed to her injuries before receiving first aid.
Babar Khan, who also got serious injuries, is admitted in Intensive Care Unit (ICU) at local hospital, however, his wife Sana didnt survive and succumbed to injuries.
The young actress dead body will be shifted to her hometown Karachi.