Microimaging centre to come up in Hyderabad

Hyderabad | Updated: Nov 29 2004, 05:30am hrs
The Centre for Cellular and Molecular Biology plans to set up a high-field, 600 MHz, biomedical magnetic resonance microimaging and spectroscopy facility by next year. The facility would reduce the number of animal killings used in pre-clinical studies.

Microimaging technique provides solutions to problems associated with biomedical research using animal models. The facility will help view images at micro levels. Images of small flies could be viewed with highest resolution, Lalji Singh, CCMB director said.

We are in the process of setting up this facility during the next financial year in association with the department of science and technology and the Council of Scientific and Industrial Research (CSIR). It will assist in research of in-vivo microimaging of transgenic and gene knockout animal models for human diseases, he said. Micro-imaging facility has the unique capabiliy of investigating non-invasively. Non-invasive imaging methods are essential for preserving precious biological specimens.

Instead of killing mice and pooling the data, we can image the mice using the required chemicals and monitor them everyday, he said. In due course, we are planning to use the high resolution facility to screen human beings, he said.

High resolution spectroscopy related to magnetic resonance imaging will make it possible to study drug target as well monitor drug response at the metabolic, physiological and cellular levels.

Meanwhile, the proposed move to set up five bio-safety-4 level (BSL) laboratories as part of CSIR-network project to monitor infectious diseases handling, storage and research facilities at an estimated cost of Rs 60-80 crore on a turnkey project basis, is being considered by the Planning Commission.