The office of President Ashraf Ghani said Friday there was "close coordination" between the U.S. military and the Afghan government on the operation, and they were careful to prevent any civilian casualties.
The US estimates 600-800 IS fighters are in Afghanistan, mostly in Nangarhar.
The US has concentrated on fighting them while also supporting Afghan forces against the Taliban. The US has more than 8,000 US troops in Afghanistan, training local forces and conducting counterterrorism operations.
(Image: Still image taken from a video released by the US Department of Defense shows the moment a MOAB struck the Achin district of the eastern province of Nangarhar, Afghanistan/Reuters)