Obese mums give birth to healthier kids after weight loss surgery
This is because the metabolic changes and weight loss that occur after the surgery have a positive effect on inflammatory disease-related genes in the offspring, the researchers explained.
“Our research found that maternal obesity affects the genes of the offspring,” said Dr. Frederic Guenard, a post-doctoral fellow under the supervision of Dr. Marie-Claude Vohl of the Functional Food Institute at Laval University and a recipient of a Heart and Stroke Foundation Research Fellowship.
“The good news is that we can do something to change this outcome: Reducing obesity in the mother has a positive health impact on the health of future offspring,” he stated.
Bariatric surgeons and researchers at Laval University observed that children born after their mothers had a type of bariatric surgery called bilio-pancreatic bypass surgery were less likely to be obese, had improved insulin resistance, lower blood pressure and an improved cardiovascular disease risk profile.
This observation prompted Dr. Guenard and his team to study the underlying reasons for this improvement in heart disease risk.
They took blood samples from 25 children of 20 mothers who were born before their mothers had bilio-pancreatic bypass surgery and blood samples from 25 of their siblings who were born afterwards.
The children ranged in age from two to 24 years. The average body mass index (BMI) of the mothers
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