Herbal stroke remedy no better than dummy pill

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SummaryChinese herbal remedy to improve stroke recovery failed to exceed benefits of placebo.

A Chinese herbal remedy marketed to improve stroke recovery failed to exceed the benefits of a placebo in a large, three-month clinical trial. "There's no evidence of efficacy," said Dr. James Brorson, medical director of the University of Chicago Stroke Center, who was not involved in the study.

Still, the researchers are not completely discouraged by the results. "Yes, we had hoped for a larger effect, but the results of the trial suggest that this may be the case for certain groups of patients," said Dr. Christopher Chen, the report's lead author and a professor at the National University of Singapore.

Chen's research was supported in part by Moleac, the company that markets the herbal medicine, called NeuroAiD. NeuroAiD is a blend of extracts from plants, leeches, beetles, scorpions and antelope horn. Some earlier studies had hinted that the compound could help people recover from an ischemic stroke, the most common kind, caused by a blood vessel blockage in the brain.

According to David Picard, the CEO of Moleac, NeuroAiD is sold in at least 25 countries, and 20,000 people have taken it. It is currently not available through U.S.-based vendors, although consumers can buy it online. A three month regimen costs about $1,500. Brorson said there is a huge need for treatments to help in stroke recovery because there is no treatment guaranteed to help repair the brain damage caused by strokes.

Chen and his colleagues decided to compare the effect of NeuroAiD to a placebo among people who had recently suffered an ischemic stroke. More than 800 people agreed to be in the study and half were randomly assigned to get NeuroAiD and the other half to a dummy medication. Neither the patients nor the doctors knew which pills each participant was taking.

For three months, all the patients took 12 capsules a day. At the beginning and end of the study, the patients' disability level was assessed based on a six-point scale called the modified Rankin scale. A score of zero to one indicates no or insignificant disability, while five is the worst and six is death.

After three months, the distribution of patients in each disability category on the scale was the same for the placebo group and the NeuroAiD group, Chen's team reports in the journal Stroke. The results mean the herbal medicine did not help people recover their function.David Picard, the CEO of Moleac, said he was not discouraged

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