Cases of advanced breast cancer inching up in young women
Yet the overall rate of cancers in that group is still small. One in 173 women will develop breast cancer before she turns 40, said researchers whose report appeared in the Journal of the American Medical Association - but the prognosis tends to be worse for younger patients.
The study, led by Rebecca Johnson at Seattle Children's Hospital and University of Washington, found that the rate of metastatic breast cancer in particular rose about two percent each year between 1976 and 2009 among younger women.
"We think that the likelihood is that since this change has been so marked over just a couple of decades, that it's something external, a modifiable lifestyle-related risk factor or perhaps an environmental toxic exposure, but we don't know what," Johnson said.
One possibility is that overeating and lack of exercise are driving up early-life metastatic breast cancer rates, Johnson added. Or, the use of hormonal birth control could play a role, she said.
But Johnson also pushed for more research into the potential effects of hormones in meat or plastic in bottles, for example.
Johnson's team analyzed data from cancer registries run by the National Cancer Institute. As expected, they found that the number of early breast cancer diagnoses increased among middle-aged and older women during the study period, likely due to widespread screening.
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