India ended down 1.5 percent.
Investors took profit across a range of blue chips. Hindalco Industries fell 4.73 percent, while Tata Motors , which had gained 6.3 percent so far this month, was down 2.4 percent.
However, Infosys Ltd rose 0.76 percent after posting a stronger-than-expected 25 percent increase in net profit.
Other IT outsourcing companies also rose, with Tata Consultancy Services gaining 4.1 percent and Wipro closing 3.6 percent higher.
Shares in United Spirits Ltd rose as much as 15 percent to a record high of 2,940.80 rupees after Diageo Plc announced a tender offer to acquire up to an additional 26 percent stake in the Indian firm at 3,030 rupees a share. The offer will be launched in June.
Shares in the spirits maker ended up 11.6 percent.