Arunachal Pradesh tribe helps in TB research breakthrough
The researchers and doctors conducted free general medical camps in five villages of Arunachal Pradesh in India and gave free medicines to all patients belonging to the Idu-Mishmis sub tribe.
This effort led to identification of individuals who had TB, and successfully completed drug treatment.
From these individuals, the team isolated the CD271+ stem cells, and found evidence of dormant TB bacteria in those stem cells.
These results supported Das's laboratory and Campos-Neto's animal study evidence that dormant TB hide in the CD271+ stem cells, the press statement said.
The findings raise the possibility that other infectious agents may employ similar "wolf-in-stem-cell-clothing" tactics.
And, although any new human treatments are likely to still be years away, they suggest a new possible target in the fight against tuberculosis, which infects nearly 2.2 billion people worldwide.
The study was carried in collaboration with scientists from the Forsyth Institute in Cambridge; Hospital for Sick Children in Toronto; and RIWATCH (Research Institute of World's Ancient Traditions Cultures and Heritage).
Ista Pulu, a Doctor belonging to Idu Mishimi community, and Vijay Swami, Director of RIWATCH are the co-authors of the paper.
Deepjyoti Kalita, a Doctor from Guwahati Medical College who participated in research study and Lab work at Roing is also a co-author from north east India. The study as to "why TB treated patients remain sensitive to TB tests for life" made a breakthrough, "the results now will have direct implications in anti-TBdrug development and explain why it is
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