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Rhythms of body clock linked to human mood disorder


Posted: 2008-09-07 22:58:54+05:30 IST
Updated: Sep 07, 2008 at 2258 hrs IST

The biological clock of humans is intricately linked with day and night. But if it falls out of sync, it can have serious psychological consequences, a new study says. Researchers at Swinburne University of Technology have studied the body clock or the circadian system and found that its rhythms can have profound effects on human mood, including triggering relapses in patients with bipolar disorder.

According to them, mood disorders such as bipolar disorder have long been linked to sleep problems, suggesting that the circadian system plays a role in these conditions. “If you take seriously this idea that the body clock is part of a causal pathway to mood disorders, then a natural deduction is that monitoring clock function might provide early warning of relapse in vulnerable people,” Greg Murray, the leader of the research team, said.

For their study, the researchers recruited 12 people with bipolar disorder and fitted them with wrist-worn devices designed to monitor their circadian system by measuring their physical activity throughout the day and night. The subjects were tracked for a year. In the next stage of research, the team wants to see if signals of rhythm disruption in patients can be used as markers of vulnerability to bipolar disorder.

AP

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