State news agency SANA said the rocket attack in Aleppo also wounded 17 people in the city's northern neighborhood of Achrafieh.
The agency said the attack was carried out by ''terrorists,'' the term the government uses to refer to rebels trying to overthrow President Bashar Assad.
It said the shells also damaged two houses in the area.
The attack came a day after similar shelling on the neighborhood killed three people and wounded 20.
Aleppo has been carved up into opposition- and government-held areas since the rebels launched an offensive there in July 2012, capturing territory along Syria's northern border with Turkey.
Rocket attacks are common on residential neighborhood around Syria. The rockets can be wildly inaccurate.
The rocket attack came shortly before a car bomb exploded outside a mosque in the northwestern town of Binish, activists said. The Britain-based Syrian Observatory for Human Rights and an activist who goes by the name of Mohammed Kanaan had no immediate word on casualties. Kanaan said the blast occurred as worshippers were at the Grand Mosque attending Friday prayers.
Activists say Syria's 3-year-old conflict has killed more than 150,000 people. More than 2.5 million people have fled Syria to neighboring countries, while millions more are displaced within it.