The 45-year-old 'Friends' star opened up about how she has coped in Hollywood all these years during an interview, reported Contactmusic.
"All that stuff, it's toxic. It never gets un-jarring, but you do have to not let it imprison you, which is possible too," she said.
Aniston said she tries to stay as much humble and grounded as possible in her successful career.
"There's times when you see people climbing and getting success and you start to see, oh, they're starting to really change. So I always just make the effort to be as humble and grateful as possible," she said.
The 'Bruce Almighty' star further said she tries to work really hard and does not shy away from taking chances.
"You just have to work really hard to tune out the noise and the static. Because it gets louder, and people really have an opinion, and you don't want to shy away from taking chances for fear of what people will say," she said.