An office of the Hamas-run Interior Ministry was located in the seven-story Zourab building. Police say seven people were wounded by the bombing of the commercial center. There were no reports of casualties from the other strike.
The strikes early today came hours after Israel toppled a 12-story apartment tower in Gaza City. Israel says it targeted a Hamas operations room in the apartment tower.
Meanwhile, the Israeli military says five rockets were fired from Syria at the Israeli-annexed Golan Heights, falling in open areas.
Amid signs of further escalation, Egypt has urged both sides to resume indirect cease-fire talks in Cairo.