Anderson died on Sunday under hospice care in Burbank, her friend Betty Landess said, according to the Los Angeles Times.
Anderson was the widow of cinematographer Leon Shamroy, who collected 18 Academy Award nominations during his career and won for 'The Black Swan' (1942), 'Wilson' (1944), 'Leave Her to Heaven' (1945) and 'Cleopatra' (1963). They were married for 21 years until his death in 1974.
While attending Howard College (now Samford University) in her native Birmingham, Alabama, Anderson was discovered by director George Cukor, who was searching for an actress to play Scarlett O'Hara in the adaptation of Margaret Mitchell's Civil War epic 'Gone With the Wind' (1939).
Cukor was fired, and the role of O'Hara went to Vivien Leigh, who went on to capture the best actress Oscar. Anderson was cast in a small role as Maybelle, Scarlett's cousin and the wife of Louisiana native Rene Picard (Alberto Morin).
In 'Lifeboat' (1944), Anderson played US Army nurse Alice Mackenzie opposite Tallulah Bankhead, William Bendix, Walter Slezak, John Hodiak and Hume Cronyn in the claustrophobic Hitchcock drama.
Anderson's film resume also includes 'Flight Angels' (1940), 'Cheers for Miss Bishop' (1941), 'Henry Aldrich for President' (1941), 'The Song of Bernadette' (1943), 'Wilson' (1944), To Each His Own (1946), The Underworld Story (1950) and 'Passage West' (1951).
She had a recurring role on ABC's 'Peyton Place' in 1964 and appeared in other such series as 'Climax!', 'Mike Hammer', 'Perry Mason', 'The Californians', 'My Three Sons and Daniel Boone'.
Her younger brother, James, an actor who appeared in 'To Kill a Mockingbird' (1962), 'Little Big Man' (1970) and the TV Westerns 'Rawhide' and 'Gunsmoke', died in 1969.