The actress took to Twitter to thank her admirers for making the film a success.
The action-thriller was directed by Mohit Suri and also marked Shraddha's singing debut on-screen and Riteish Deshmukh's first negative role.
"Feeling really good, all thanks to you guys. Finally 'Ek Villain' has crossed 100 crore mark, which means so many of you have actually gone and watched the film and shown your love.
"Thank you so much from the bottom of my heart for enjoying it and for all the love and appreciation," Shraddha said in a three-and-a half minute YouTube video.
The actress dedicated her hit number 'Galliyan Unplugged' from the film to her fans in the video.
Shraddha's last release 'Aashiqui 2' opposite Aditya Roy Kapur also crossed the 100 crore mark.