The 30-share barometer declined by 27.44 points, or 0.12 per cent, to 22,660.63. The index had lost 188.47 points on Friday.
Stocks of auto, PSUs, banking, FMCG and power sectors were the major losers.
Similarly, the NSE Nifty also fell by 15.35 points, or 0.23 per, to 6,767.40.
Brokers said selling, mostly of a profit-booking nature, by participants at current levels amid forecast of below normal monsoon this year, mainly influenced the trading sentiments here.
They said, a weak trend on other Asian bourses on concerns about Ukraine tensions, too triggered selling.
Among other Asian markets, Japan's Nikkei was down 1.15 per cent, while Hong Kong's Hang Seng shed 0.46 per cent in early trade today.