The 20-year-old actress is replacing the previously-cast Amy Forsyth in 'Scream' as teen filmmaker Audrey Jensen, reported Deadline.
Audrey Jensen is the ex-best friend of Willa Fitzgerald's character Emma Duval, who has recently been accepted among her school's popular clique.
Taylor-Klaus has played The Canary's sidekick Sin in 'Arrow', and has also appeared in 'The Killing as Bullet'.
'Scream's small screen adaptation begins with the release of a viral video that exposes a town's dark secrets and sets up a brutal murder.
Also joining the cast are Bobby Campo (Being Human USA) as English teacher Seth Branson, Joel Gretsch (The 4400) as Sheriff Clark Hudson and Connor Weil (Sharknado) as Emma's basketball-playing boyfriend Will Belmont.
'Scream' is expected to premiere on MTV in 2015.