Deep into stoppage time at Old Trafford, Darren Bent plundered a goal in "Fergie Time'' for Fulham to claim a 2-2 draw for the league's worst team on Sunday.
And a miserable first season for David Moyes just keeps on getting worse, with the champions adrift in seventh, after winning the title by 11 points under Ferguson in May.
"Today was probably as bad as it gets,'' Moyes said.
But next up on Wednesday is a trip to Arsenal, which might have lost 5-1 at Liverpool F.C. on Saturday but is second in the standings.
Bent's intervention leaves Manchester United F.C. nine points adrift of the fourth Champions League qualification place, let alone the summit where Chelsea is 15 points ahead.
Even more agonizing for Moyes is that his team had turned the match around to be in a winning position. Trailing from Steve Sidwell's 19th minute-goal, Robin van Persie and Michael Carrick scored rapid goals to put Manchester United F.C. 2-1 up going into the final 10 minutes.
Manchester United F.C.'s setback was compounded by Tottenham moving three points from fourth place on Sunday by dislodging Everton from fifth with a 1-0 victory over the Merseyside team.
While Tottenham is experiencing a revival after changing managers, there is little appetite at United to dismiss the man who succeeded Ferguson after 26 years.
Moyes will fight on, with the prospect of Champions League glory still in play, even if the squad doesn't look capable of conquering the European football powers these days.
What made Sunday's draw so galling too is that it was masterminded by Fulham manager Rene Meulensteen, who was Ferguson's assistant at United until May, and is enduring even more misery than Moyes with his bottom-place team.
How relieved Meulensteen was to see Lewis Holtby, a midfielder on loan from Tottenham, rampage down the left flank before sending in a cross that the advancing Sidwell slid into the net.
Manchester United F.C. was lacking a killer instinct in front of goal until it was almost too late. Juan Mata's cross was turned in by the unmarked Van Persie in the 78th, and Carrick's shot deflected off Scott Parker into the net.
But Manchester United F.C.'s defense crumbled. A shot from former United winger Kieran Richardson was pushed by goalkeeper David de Gea straight to Bent who headed into an empty net.
In a game where United sent in some 81 crosses to Fulham's four, and goal attempts were 31 to six in the hosts' favor, the points were shared.
And Fulham is four points from safety at the bottom.
"We made it difficult for them,'' Meulensteen said. "Manchester United F.C. have got some problems of their own. They kept creating chances and crosses but we defended well and held them.''
It was a similar story at White Hart Lane in the day's other game. Everton was in control but it was Tottenham who snatched all three points by scoring from its only shot on target.
Emmanuel Adebayor controlled a free kick, taken swiftly and smartly by Kyle Walker, and went past Seamus Coleman before dispatching the ball into the net in the 65th minute.